Human NEK6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEK6
Locus ID	10783
Kit Components	GA107389G1, NEK6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107389G2, NEK6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107389G3, NEK6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145001, NM_001166167, NM_001166168, NM_001166169, NM_001166170, NM_001166171, NM_014397
Synonyms	SID6-1512
Summary	The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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