Human LILRB4 activation kit by CRISPRa

CAT#: GA107557

LILRB4 CRISPRa kit - CRISPR gene activation of human leukocyte immunoglobulin like receptor B4



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
LILRB4 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


LILRB4 (Myc-DDK-tagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4), transcript variant 1
    • 10 ug

CNY 5,488.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol LILRB4
Locus ID 11006
Kit Components

GA107557G1, LILRB4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107557G2, LILRB4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107557G3, LILRB4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001081438, NM_001278426, NM_001278427, NM_001278428, NM_001278429, NM_001278430, NM_006847
Synonyms CD85K; HM18; ILT3; LILRB5; LIR-5; LIR5
Summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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