Human PADI2 activation kit by CRISPRa

CAT#: GA107744

PADI2 CRISPRa kit - CRISPR gene activation of human peptidyl arginine deiminase 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-PADI2 Antibody
    • 50 ug

CNY 4,628.00


PADI2 (Myc-DDK-tagged)-Human peptidyl arginine deiminase, type II (PADI2)
    • 10 ug

CNY 4,952.00
CNY 5,800.00


PADI2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PADI2
Locus ID 11240
Kit Components

GA107744G1, PADI2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107744G2, PADI2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107744G3, PADI2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_007365
Synonyms PAD-H19; PAD2; PDI2
Summary This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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