Human RIM1 (RIMS1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIMS1
Locus ID	22999
Kit Components	GA107960G1, RIM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107960G2, RIM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107960G3, RIM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001168407, NM_001168408, NM_001168409, NM_001168410, NM_001168411, NM_014989, NM_001350411, NM_001350412, NM_001350413, NM_001350414, NM_001350415, NM_001350416, NM_001350417, NM_001350418, NM_001350419, NM_001350420, NM_001350421, NM_001350422, NM_001350423, NM_001350424, NM_001350425, NM_001350426, NM_001350427, NM_001350428, NM_001350429, NM_001350430, NM_001350431, NM_001350432, NM_001350433, NM_001350434, NM_001350435, NM_001350436, NM_001350437, NM_001350438, NM_001350439, NM_001350440, NM_001350441, NM_001350442, NM_001350443, NM_001350444, NM_001350445, NM_001350446, NM_001350447, NM_001350448, NM_001350449, NM_001350450, NM_001350452, NM_001350454, NM_001350455, NM_001350456, NM_001350457, NM_001350458, NM_001350459, NM_001350460, NM_001350461, NM_001350462, NM_001350463, NM_001350464, NM_001350465, NM_001350466, NM_001350467, NM_001350468, NM_001350469, NM_001350470, NM_001350471, NM_001350472, NM_001350473, NM_001350474
Synonyms	CORD7; RAB3IP2; RIM; RIM1
Summary	The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

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