Human ERC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERC1
Locus ID	23085
Kit Components	GA108025G1, ERC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108025G2, ERC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108025G3, ERC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001301248, NM_015064, NM_032684, NM_178037, NM_178038, NM_178039, NM_178040, NR_027946, NR_027948, NR_027949
Synonyms	Cast2; ELKS; ERC-1; RAB6IP2
Summary	The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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