Human SIRT5 activation kit by CRISPRa

CAT#: GA108286

SIRT5 CRISPRa kit - CRISPR gene activation of human sirtuin 5



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SIRT5 mouse monoclonal antibody, clone OTI2F1 (formerly 2F1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


SIRT5 (Myc-DDK-tagged)-Human sirtuin 5 (SIRT5), transcript variant 1
    • 10 ug

CNY 3,600.00
CNY 4,465.00


SIRT5 mouse monoclonal antibody, clone OTI1B6 (formerly 1B6)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SIRT5
Locus ID 23408
Kit Components

GA108286G1, SIRT5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108286G2, SIRT5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108286G3, SIRT5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001193267, NM_001242827, NM_012241, NM_031244
Synonyms SIR2L5
Summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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