Human TNFAIP8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFAIP8
Locus ID	25816
Kit Components	GA108556G1, TNFAIP8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108556G2, TNFAIP8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108556G3, TNFAIP8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001077654, NM_001286813, NM_001286814, NM_001286815, NM_001286817, NM_014350
Synonyms	GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Summary	Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.[UniProtKB/Swiss-Prot Function]

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