Human DFNB31 (WHRN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WHRN
Locus ID	25861
Kit Components	GA108591G1, DFNB31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108591G2, DFNB31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108591G3, DFNB31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001083885, NM_001173425, NM_015404, NM_001346890
Synonyms	CIP98; PDZD7B; USH2D; WHRN; WI
Summary	This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

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