Human COBRA1 (NELFB) activation kit by CRISPRa
CAT#: GA108630
NELFB CRISPRa kit - CRISPR gene activation of human negative elongation factor complex member B
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | NELFB |
Locus ID | 25920 |
Kit Components | GA108630G1, COBRA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108630G2, COBRA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108630G3, COBRA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_015456 |
Synonyms | COBRA1; NELF-B |
Summary | NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN413518 | NELFB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |