Human TPK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TPK1
Locus ID	27010
Kit Components	GA108964G1, TPK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108964G2, TPK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108964G3, TPK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042482, NM_022445, NM_001350879, NM_001350880, NM_001350881, NM_001350882, NM_001350883, NM_001350884, NM_001350885, NM_001350886, NM_001350887, NM_001350889, NM_001350893, NM_001350894, NM_001350895, NR_146935, NR_146936, NR_146934
Synonyms	HTPK1; PP20; THMD5
Summary	The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]

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