Human RACGAP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RACGAP1
Locus ID	29127
Kit Components	GA109257G1, RACGAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109257G2, RACGAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109257G3, RACGAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001126103, NM_001126104, NM_001319999, NM_001320000, NM_001320001, NM_001320002, NM_001320003, NM_001320004, NM_001320005, NM_001320006, NM_001320007, NM_013277
Synonyms	CYK4; HsCYK-4; ID-GAP; MgcRacGAP
Summary	This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]

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