Human Nucleoside Diphosphate Kinase 7 (NME7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NME7
Locus ID	29922
Kit Components	GA109312G1, Nucleoside Diphosphate Kinase 7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109312G2, Nucleoside Diphosphate Kinase 7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109312G3, Nucleoside Diphosphate Kinase 7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_013330, NM_197972, NR_104229
Synonyms	CFAP67; MN23H7; NDK 7; NDK7; nm23-H7
Summary	This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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