Human PNPLA8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PNPLA8
Locus ID	50640
Kit Components	GA109439G1, PNPLA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109439G2, PNPLA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109439G3, PNPLA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256007, NM_001256008, NM_001256009, NM_001256010, NM_001256011, NM_015723, N57453
Synonyms	IPLA2(GAMMA); IPLA2-2; IPLA2G; iPLA2gamma
Summary	This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]

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