Human GODZ (ZDHHC3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZDHHC3
Locus ID	51304
Kit Components	GA109723G1, GODZ gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109723G2, GODZ gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109723G3, GODZ gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001135179, NM_001135180, NM_016598, NM_001330761, NM_001349376, NM_001349377, NM_001349378, NM_001349379, NM_001349380, NM_001349381, NR_146161, NR_146162, NR_146163
Synonyms	DHHC-3; GODZ; ZNF373
Summary	Palmitoyltransferase with broad specificity (PubMed:21926431, PubMed:23034182). Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability (By similarity). Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25 (By similarity).[UniProtKB/Swiss-Prot Function]

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