Human RTEL1 activation kit by CRISPRa
CAT#: GA109973
RTEL1 CRISPRa kit - CRISPR gene activation of human regulator of telomere elongation helicase 1
CNY 12,255.00
CNY 21,565.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | RTEL1 |
Locus ID | 51750 |
Kit Components | GA109973G1, RTEL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109973G2, RTEL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109973G3, RTEL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001283009, NM_001283010, NM_016434, NM_032957 |
Synonyms | C20orf41; DKCA4; DKCB5; NHL; RTEL |
Summary | This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN214507 | RTEL1 - human gene knockout kit via CRISPR, HDR mediated |
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KN214507BN | RTEL1 - human gene knockout kit via CRISPR, HDR mediated |
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KN214507LP | RTEL1 - human gene knockout kit via CRISPR, HDR mediated |
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KN214507RB | RTEL1 - human gene knockout kit via CRISPR, HDR mediated |
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