Human ZA20D3 (ZFAND6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZFAND6
Locus ID	54469
Kit Components	GA110120G1, ZA20D3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110120G2, ZA20D3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110120G3, ZA20D3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242911, NM_001242912, NM_001242913, NM_001242914, NM_001242915, NM_001242916, NM_001242917, NM_001242918, NM_001242919, NM_019006
Synonyms	AWP1; ZA20D3; ZFAND5B
Summary	Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).[UniProtKB/Swiss-Prot Function]

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