Human TMEM106B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM106B
Locus ID	54664
Kit Components	GA110213G1, TMEM106B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110213G2, TMEM106B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110213G3, TMEM106B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001134232, NM_018374
Synonyms	FLJ11273; MGC33727
Summary	Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.[UniProtKB/Swiss-Prot Function]

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