Human TRPM4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRPM4
Locus ID	54795
Kit Components	GA110264G1, TRPM4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110264G2, TRPM4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110264G3, TRPM4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001195227, NM_001321281, NM_001321282, NM_001321283, NM_001321285, NM_017636
Synonyms	hTRPM4; LTrpC4; PFHB1B; TRPM4B
Summary	The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016]

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