Human SYTL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYTL2
Locus ID	54843
Kit Components	GA110304G1, SYTL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110304G2, SYTL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110304G3, SYTL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001162951, NM_001162952, NM_001162953, NM_001289608, NM_001289609, NM_001289610, NM_017695, NM_032379, NM_032943, NM_206927, NM_206928, NM_206929, NM_206930, NM_001365826, NM_001365828, NM_001365833, NM_001365827, NM_001365829, NM_001365830, NM_001365831, NM_001365832, NM_001365834, NM_001365835
Synonyms	CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A
Summary	The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jun 2009]

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