Human DET1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DET1
Locus ID	55070
Kit Components	GA110492G1, DET1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110492G2, DET1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110492G3, DET1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001144074, NM_017996, NR_026645, NM_001321594, NM_001321596, NR_135739, NR_135740, NR_135741, NR_135742, NR_135743, NR_135744
Synonyms	FLJ10103; MGC126156; MGC126157
Summary	Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.[UniProtKB/Swiss-Prot Function]

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