Human RIC8 (RIC8B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIC8B
Locus ID	55188
Kit Components	GA110588G1, RIC8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110588G2, RIC8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110588G3, RIC8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001330145, NM_001330146, NM_001330147, NM_018157, NM_001351361, NM_001351362, NM_001351363, NM_001351364, NM_001351366, NM_001351367, NR_147131, NR_147132, NR_147133, NR_147134, NR_147135, NR_147136, NR_147137, NR_147138, NR_147139
Synonyms	hSyn; RIC8
Summary	Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction.[UniProtKB/Swiss-Prot Function]

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