Human MAML3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAML3
Locus ID	55534
Kit Components	GA110781G1, MAML3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110781G2, MAML3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110781G3, MAML3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018717
Synonyms	CAGH3; ERDA3; GDN; MAM-2; MAM2; TNRC3
Summary	Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.[UniProtKB/Swiss-Prot Function]

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