Human NSUN5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NSUN5
Locus ID	55695
Kit Components	GA110889G1, NSUN5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110889G2, NSUN5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110889G3, NSUN5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001168347, NM_001168348, NM_018044, NM_148956
Synonyms	NOL1; NOL1R; NSUN5A; p120; p120(NOL1); WBSCR20; WBSCR20A
Summary	This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

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