Human CNOT6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CNOT6
Locus ID	57472
Kit Components	GA111517G1, CNOT6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111517G2, CNOT6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111517G3, CNOT6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001303241, NM_015455, NM_001370472, NM_001370473, NM_001370474, NR_163437, NR_163438
Synonyms	CCR4; Ccr4a
Summary	This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]

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