Human DPP10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DPP10
Locus ID	57628
Kit Components	GA111645G1, DPP10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111645G2, DPP10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111645G3, DPP10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001004360, NM_001178034, NM_001178036, NM_001178037, NM_001321905, NM_001321906, NM_001321907, NM_001321908, NM_001321909, NM_001321910, NM_001321911, NM_001321912, NM_001321913, NM_001321914, NM_020868, N47251
Synonyms	DPL2; DPPY; DPRP-3; DPRP3
Summary	This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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