Human Junctional Adhesion Molecule 2 (JAM2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JAM2
Locus ID	58494
Kit Components	GA111777G1, Junctional Adhesion Molecule 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111777G2, Junctional Adhesion Molecule 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111777G3, Junctional Adhesion Molecule 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001270407, NM_001270408, NM_021219, NR_072999
Synonyms	C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
Summary	This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]

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