Human EDA2R activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EDA2R
Locus ID	60401
Kit Components	GA111845G1, EDA2R gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111845G2, EDA2R gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111845G3, EDA2R gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199687, NM_001199688, NM_001199689, NM_001242310, NM_001324199, NM_001324201, NM_001324202, NM_001324204, NM_001324205, NM_001324206, NM_021783, NR_136726, NR_136727
Synonyms	EDA-A2R; EDAA2R; TNFRSF27; XEDAR
Summary	The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]

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