Human RIC3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIC3
Locus ID	79608
Kit Components	GA112486G1, RIC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112486G2, RIC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112486G3, RIC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001135109, NM_001206671, NM_001206672, NM_024557, NR_045405, NM_001346690, NM_001346691, NM_001346692, NM_001346693, NM_001346694, NR_144484, NR_144485, NR_144497
Synonyms	AYST720; PRO1385
Summary	This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

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