Human Dehydrodolichyl Diphosphate Synthase (DHDDS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DHDDS
Locus ID	79947
Kit Components	GA112748G1, Dehydrodolichyl Diphosphate Synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112748G2, Dehydrodolichyl Diphosphate Synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112748G3, Dehydrodolichyl Diphosphate Synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001243564, NM_001243565, NM_001319959, NM_024887, NM_205861
Synonyms	CIT; CPT; DS; HDS; RP59
Summary	The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

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