Human C13orf18 (RUBCNL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RUBCNL
Locus ID	80183
Kit Components	GA112855G1, C13orf18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112855G2, C13orf18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112855G3, C13orf18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001286761, NM_001286762, NM_001286763, NM_001286764, NM_001286765, NM_001286766, NM_025113, NM_001349772
Synonyms	C13orf18; KIAA0226L
Summary	This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]

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