Human SHKBP1 activation kit by CRISPRa
CAT#: GA114242
SHKBP1 CRISPRa kit - CRISPR gene activation of human SH3KBP1 binding protein 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SHKBP1 |
Locus ID | 92799 |
Kit Components | GA114242G1, SHKBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114242G2, SHKBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114242G3, SHKBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_138392 |
Synonyms | PP203; Sb1 |
Summary | Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404760 | SHKBP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |