Human MRAP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MRAP2
Locus ID	112609
Kit Components	GA114359G1, MRAP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114359G2, MRAP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114359G3, MRAP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_138409, NM_001346541, NM_001346542, NM_001346543, NM_001346544
Synonyms	bA51G5.2; BMIQ18; C6orf117
Summary	This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]

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