Human Porimin (TMEM123) activation kit by CRISPRa

CAT#: GA114494

TMEM123 CRISPRa kit - CRISPR gene activation of human transmembrane protein 123



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-TMEM123 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TMEM123 (Myc-DDK-tagged)-Human transmembrane protein 123 (TMEM123)
    • 10 ug

CNY 2,400.00
CNY 3,705.00


Rabbit Polyclonal Anti-TMEM123 Antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol TMEM123
Locus ID 114908
Kit Components

GA114494G1, Porimin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114494G2, Porimin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114494G3, Porimin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_052932
Synonyms KCT3; PORIMIN; PORMIN
Summary This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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