Human PIK3AP1 activation kit by CRISPRa

CAT#: GA114672

PIK3AP1 CRISPRa kit - CRISPR gene activation of human phosphoinositide-3-kinase adaptor protein 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PIK3AP1 mouse monoclonal antibody, clone OTI7A11 (formerly 7A11)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PIK3AP1 (Myc-DDK-tagged)-Human phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1)
    • 10 ug

CNY 5,896.00
CNY 8,460.00


PIK3AP1 biotinylated mouse monoclonal detection antibody, validated for Luminex assays
    • 50 ug

CNY 2,700.00
CNY 3,790.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PIK3AP1
Locus ID 118788
Kit Components

GA114672G1, PIK3AP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114672G2, PIK3AP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114672G3, PIK3AP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_152309
Synonyms BCAP
Summary Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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