Human C22orf25 (TANGO2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TANGO2
Locus ID	128989
Kit Components	GA115072G1, C22orf25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115072G2, C22orf25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115072G3, C22orf25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001283106, NM_001283116, NM_001283129, NM_001283148, NM_001283154, NM_001283179, NM_001283186, NM_001283199, NM_001283215, NM_001283235, NM_001283248, NM_001322141, NM_001322142, NM_001322143, NM_001322144, NM_001322145, NM_001322146, NM_001322147, NM_001322148, NM_001322149, NM_001322150, NM_001322153, NM_001322155, NM_001322160, NM_001322163, NM_001322166, NM_001322167, NM_001322169, NM_001322171, NM_001322172, NM_001322173, NM_001322174, NM_001322175, NM_152906, NR_104274, NR_104275, NR_136206, NR_136211, NR_136212
Synonyms	C22orf25; MECRCN
Summary	This gene belongs to the transport and Golgi organization family, whose members are predicted to play roles in secretory protein loading in the endoplasmic reticulum. Depletion of this gene in Drosophila S2 cells causes fusion of the Golgi with the ER. In mouse tissue culture cells, this protein co-localizes with a mitochondrially targeted mCherry protein and displays very low levels of co-localization with Golgi and peroxisomes. Allelic variants of this gene are associated with rhabdomyolysis, metabolic crises with encephalopathy, and cardiac arrhythmia. [provided by RefSeq, Apr 2016]

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