Human Activin A Receptor Type IC (ACVR1C) activation kit by CRISPRa
CAT#: GA115111
ACVR1C CRISPRa kit - CRISPR gene activation of human activin A receptor type 1C
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ACVR1C |
Locus ID | 130399 |
Kit Components | GA115111G1, Activin A Receptor Type IC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115111G2, Activin A Receptor Type IC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115111G3, Activin A Receptor Type IC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001111031, NM_001111032, NM_001111033, NM_145259 |
Synonyms | ACVRLK7; ALK7 |
Summary | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN405434 | ACVR1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |