Human ZNF420 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZNF420
Locus ID	147923
Kit Components	GA115639G1, ZNF420 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115639G2, ZNF420 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115639G3, ZNF420 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_144689, NM_001329515, NM_001329516, NM_001329517, NM_001329518, NM_001329519, NM_001329520, NM_001329521, NM_001329522, NM_001329524, NR_138039
Synonyms	APAK
Summary	The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]

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