Human FAM119A (METTL21A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	METTL21A
Locus ID	151194
Kit Components	GA115781G1, FAM119A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115781G2, FAM119A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115781G3, FAM119A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001127395, NM_001308021, NM_001330130, NM_001330131, NM_001330132, NM_001330133, NM_001330134, NM_001330135, NM_001330136, NM_001330137, NM_145280
Synonyms	FAM119A; HCA557b; HSPA-KMT
Summary	Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.[UniProtKB/Swiss-Prot Function]

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