Human TMEM65 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM65
Locus ID	157378
Kit Components	GA115920G1, TMEM65 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115920G2, TMEM65 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115920G3, TMEM65 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_194291
Synonyms	2610029O13Rik; 4930438D12Rik; OTTMUSP00000023023; transmembrane protein 65
Summary	May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (By similarity). May also play a role in the regulation of mitochondrial respiration and mitochondrial DNA copy number maintenance (PubMed:28295037).[UniProtKB/Swiss-Prot Function]

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