Human FREM1 activation kit by CRISPRa
CAT#: GA115955
FREM1 CRISPRa kit - CRISPR gene activation of human FRAS1 related extracellular matrix 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | FREM1 |
Locus ID | 158326 |
Kit Components | GA115955G1, FREM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115955G2, FREM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115955G3, FREM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001177704, NM_144966, NM_001370060, NM_001370061, NM_001370065, NR_163239, NR_163240, NR_163241, NM_001370058, NM_001370063, NR_163238, NR_163242 |
Synonyms | BNAR; C9orf143; C9orf145; C9orf154; MOTA; TILRR; TRIGNO2 |
Summary | This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN422886 | FREM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |