Human TOR1AIP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TOR1AIP2
Locus ID	163590
Kit Components	GA116092G1, TOR1AIP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116092G2, TOR1AIP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116092G3, TOR1AIP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199260, NM_022347, NM_145034, NM_001349931, NM_001349933, NM_001349934, NM_001349935, NM_001349936, NM_001349937
Synonyms	IFRG15; LULL1; NET9
Summary	One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]

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