Human CCDC46 (CEP112) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CEP112
Locus ID	201134
Kit Components	GA116374G1, CCDC46 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116374G2, CCDC46 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116374G3, CCDC46 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001037325, NM_001199165, NM_001302891, NM_145036, NR_126542, NM_001353127, NM_001353128, NM_001353129
Synonyms	CCDC46; MACOCO
Summary	This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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