Human ZDHHC20 activation kit by CRISPRa
CAT#: GA116759
ZDHHC20 CRISPRa kit - CRISPR gene activation of human zinc finger DHHC-type containing 20
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ZDHHC20 |
Locus ID | 253832 |
Kit Components | GA116759G1, ZDHHC20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116759G2, ZDHHC20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116759G3, ZDHHC20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001286638, NM_001330059, NM_153251, NR_104486, NR_104487 |
Synonyms | 4933421L13Rik; DHHC-20 |
Summary | Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN415317 | ZDHHC20 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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