Human POLDIP1 (KCTD13) activation kit by CRISPRa
CAT#: GA116763
KCTD13 CRISPRa kit - CRISPR gene activation of human potassium channel tetramerization domain containing 13
CNY 12,255.00
CNY 1,999.00
CNY 2,700.00
CNY 3,600.00
CNY 800.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | KCTD13 |
Locus ID | 253980 |
Kit Components | GA116763G1, POLDIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116763G2, POLDIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116763G3, POLDIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_178863, NR_110933 |
Synonyms | BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1 |
Summary | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN406944 | KCTD13 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |