Human MAP1D (METAP1D) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	METAP1D
Locus ID	254042
Kit Components	GA116766G1, MAP1D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116766G2, MAP1D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116766G3, MAP1D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001322278, NM_001322279, NM_199227, NR_136273, NR_136276
Synonyms	MAP 1D; MAP1D; MetAP 1D; Metap1l
Summary	The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]

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