Human PP14397 (JMJD8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JMJD8
Locus ID	339123
Kit Components	GA117401G1, PP14397 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117401G2, PP14397 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117401G3, PP14397 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001005920, NM_001323918, NM_001323919, NM_001323920, NM_001323922, NR_136650, NR_136651, NR_136652
Synonyms	C16orf20; PP14397
Summary	Functions as a positive regulator of TNF-induced NF-kappa-B signaling (PubMed:27671354). Regulates angiogenesis and cellular metabolism through interaction with PKM (PubMed:27199445).[UniProtKB/Swiss-Prot Function]

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