Human carabin (TBC1D10C) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TBC1D10C
Locus ID	374403
Kit Components	GA117765G1, carabin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117765G2, carabin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117765G3, carabin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256508, NM_198517, NR_046266, NM_001369492, NM_001369494, NM_001369496, NM_001369497, NM_001369495, NM_001369498
Synonyms	CARABIN; EPI64C
Summary	The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

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