Human Agrin (AGRN) activation kit by CRISPRa
CAT#: GA117836
AGRN CRISPRa kit - CRISPR gene activation of human agrin
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | AGRN |
Locus ID | 375790 |
Kit Components | GA117836G1, Agrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117836G2, Agrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117836G3, Agrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001305275, NM_198576, NM_001364727 |
Synonyms | CMS8; CMSPPD |
Summary | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN412203 | AGRN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |