Human CDK11A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDK11A
Locus ID	728642
Kit Components	GA118961G1, CDK11A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118961G2, CDK11A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118961G3, CDK11A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001313896, NM_001313982, NM_024011, NM_033529, NR_132739, NR_132740
Synonyms	CDC2L2; CDC2L3; CDK11-p46; CDK11-p58; CDK11-p110; p58GTA; PITSLRE
Summary	This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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