Mouse Chrna7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrna7
Locus ID	11441
Kit Components	GA200034G1, Chrna7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200034G2, Chrna7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200034G3, Chrna7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007390
Synonyms	Acra7; alpha7; nAchR
Summary	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.[UniProtKB/Swiss-Prot Function]

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